Chronic toxicity of 2,4,6-tri-tert-butylphenol in rats.

Screening Assessment for the Challenge Phenol, 2,4,6-tris(1,1-dimethylethyl)- (2,4,6-tri-tert-butylphenol)

Sub-Chronic Toxicity Study of Alpha-Cypermethrin in Rats

Alpha-cypermethrin (?-CP) a synthetic pyrethroid (type-II) insecticide, dissolved in dimethyl sulfoxide (DMSO-1ml) given consecutive daily orally for 60 days at 1/10LD50 (14.5mg/kg). The animals were sacrificed on day 61st. Biochemicals, cytochromeP450, b5 contents in liver along with antioxidant status, tissue residual concentration, and brain GABA level were studied. It increased the serum am...

Ammonium tri-tert-butoxy­silanethiol­ate

The cations and anions of the title salt, NH(4) (+)·C(12)H(27)O(3)SSi(-), are linked by N-H⋯S and N-H⋯O hydrogen bonds into a linear chain that runs along the a axis of the monoclinic unit cell. The asymmetric unit contains two cations and two anions.

Antioxidative Activity of Ferrocenes Bearing 2,6-Di-Tert-Butylphenol Moieties

The antioxidative activity of ferrocenes bearing either 2,6-di-tert-butylphenol or phenyl groups has been compared using DPPH (1,1-diphenyl-2-picrylhydrazyl) test and in the study of the in vitro impact on lipid peroxidation in rat brain homogenate and on some characteristics of rat liver mitochondria. The results of DPPH test at 20 degrees C show that the activity depends strongly upon the pre...

Chronic Toxicity Study of Neosaxitoxin in Rats

Neosaxitoxin (NeoSTX) is a specific reversible blocker of voltage gated sodium channels on excitable cells. In the last decade, it has been tested in a number of interesting clinical trials, however there is still little information available on mammalian toxicity. Rats were treated for 12 weeks with doses of 1, 3 or 6 μg/kg of subcutaneous NeoSTX. At weeks 12 and 17, animals were sacrificed an...